We can determine pharmacokinetics in plasma, sera, blood and tissues using various routes of administration including techniques for continuous administration. Tissue distribution studies and mass balance studies using radioactive-labeled compounds can be performed in-house.
Standard equipment in use in our bioanalytical unit include HPLC-UV, HPLC-UV-Fluorescence as well as the triple-quadruple mass spectrograph HPLC-MS/MS from Agilent/AB SCIEX, and the HPLC-UV radiomonitor-MSn from Shimadzu for radiomarker analysis. SOP controlled R&D processes ensure high quality and reproducible data generation, which are reported in accordance with regulatory standards.
Last but not least, Heidelberg Pharma offers synthesis of major metabolites of your compound to test these in vitro and in vivo for determining their biological activity profile.
Please find more information below: